Where is First Presbyterian Church located?

First Presbyterian Church is at 10790 Business 21, Hillsboro, MO, 63050-5220.

What time are services at First Presbyterian Church?

First Presbyterian Church meets Sunday at 10:30am. Times are the church's local time — confirm with the church before visiting.

What denomination is First Presbyterian Church?

First Presbyterian Church in Hillsboro, MO is a Presbyterian church.

First Presbyterian Church

First Presbyterian Church is a Presbyterian church at 10790 Business 21 in Hillsboro, MO 63050-5220. It is one of 23 churches in Hillsboro.

We are an inclusive community inspired by Jesus’ way of love and justice, called to grow, transform, and serve all.

First Presbyterian Church of St. Louis is a multi-generational, multicultural, social justice–seeking church with a big heart.

Accessible parking · Part of Giddings-Lovejoy Presbytery

10790 Business 21, Hillsboro, MO, 63050-5220

Service times

Sunday 10:30am

Phone: (636) 789-2445 · Website: https://www.firstpresbyterianstl.com/

First Presbyterian Church is part of the Presbyterian family of churches in The American Church Story. 218 congregations of the Presbyterian family gather across Missouri — 11,638 across the United States on The Church Map.

Presbyterians gave American Christianity much of its backbone: seminaries, catechisms, and shared government by elders rather than by one man, a habit that shaped the country's civic life as much as its churches. They have been among the most persistent builders of colleges, hospitals, and mission agencies this nation has.

Find First Presbyterian Church on The Church Map, explore nearby congregations, and pray for its community.

Watch

Latest from First Pres St. Louis's YouTube channel: FPC Sermon August 30, 2026 (all videos).

The community around First Presbyterian Church

In the few miles around this church, more than 4 in 10 adults live with obesity. Nearly a quarter of adults say they are socially isolated, and nearly a quarter of adults here carry depression. That is two thousand neighbors — and some of them are already in these pews.

Pray for healing in the homes around this building, and for this church to be known as a place to bring what hurts.

Obesity: 40.1%
Social Isolation: 29.5%
Depression: 24.1%

Source: CDC PLACES (2023), aggregated across 4 census tracts near this church.

Churches near First Presbyterian Church

The Church of Jesus Christ of Latter-day Saints — 0.2 mi away
Covenant Life Church — 0.3 mi away
Assembly of God Church — 0.5 mi away
New Hope Fellowship — 0.5 mi away
Christ's Church of Hillsboro — 0.6 mi away
Good Shepherd Catholic Church — 0.6 mi away
Hillsboro United Methodist Church — 0.6 mi away
First Baptist Church — 0.7 mi away
Peace Tabernacle Church — 0.7 mi away
Hillsboro Christian Church — 0.9 mi away

More Presbyterian churches nearby

Grace Presbyterian Church — 10.3 mi away in Crystal City, MO
Hillside Presbyterian Church — 11.3 mi away in House Springs, MO
Spring Hills Presbyterian Church — 14.6 mi away in Byrnes Mill, MO
Good Shepherd Presbyterian Church — 20.5 mi away in St Louis, MO
Heritage Presbyterian Church — 21.9 mi away in Wildwood, MO

See all churches in Hillsboro, MO · All churches in Missouri